The journey to cure human disease frequently involves re-creating the hallmarks of that disease in an animal. However, promising medical advances in animal models seldom translate into treatments for humans. Over the last decade, significant advancements in reprogramming basic human cells (induced pluripotent stem cells, iPSC) from both healthy and diseased donors into any desired cell type has laid the foundation for the exploration of human disease in vitro. Disease mechanisms and treatments can now be explored in a more human-relevant model at higher throughputs thus advancing discoveries and therapies at an unprecedented rate.
Here, we present examples of diseases of neural or cardiac origin that are being examined, tested and treated because of insights gained from Axion's MEA technology.